[997] in Humor

home help back first fref pref prev next nref lref last post

HUMOR: A followup...

daemon@ATHENA.MIT.EDU (Andrew A. Bennett)
Thu Aug 3 18:23:07 1995

To: humor@MIT.EDU
Date: Thu, 03 Aug 1995 18:17:24 EDT
From: "Andrew A. Bennett" <abennett@MIT.EDU>


Date: Thu, 03 Aug 1995 16:07:15 +0000 (GMT)
From: Espacionaute Spiff domine! <MATOSSIAN@aries.colorado.edu>
From: bostic@bsdi.com (Keith Bostic)
From: hunter@work.nlm.nih.gov (Larry Hunter)

Re: the "Unusual Side Effects of Clomipramine..."

The article you reference has apparently not yet appeared.  However, there
are similar reports that have been published about fluoxetine (Prozac):

  Klein DF "Repeated observations of yawning, clitoral engorgement, and
  orgasm associated with fluoxetine administration" J Clin Psychopharmacol
  1989 Oct;9(5):384 -- see also comment: J Clin Psychopharmacol 1989
  Feb;9(1):63-5

  Morris PL "Fluoxetine and orgasmic sexual experiences."  Int J Psychiatry
  Med 1991;21(4):379-82

  Abstract: The purpose of this article to describe a unique potential
  side effect of fluoxetine. A case report of a patient with post stroke
  depression treated with fluoxetine is presented. Fluoxetine was
  associated temporally with frequent short episodes of sexual excitement
  described by the patient as feeling like an orgasm.  The relationship
  was dose dependent. Serotonergic medications, like fluoxetine, may
  induce sexual stimulation as a side effect.  The mechanism for this
  effect is unclear but patients with organic brain disease may be at
  higher risk for this complication.

  Garcia-Campayo J; Sanz-Carrillo C; Lobo A; "Orgasmic sexual experiences
  as a side effect of fluoxetine: a case report."  Acta Psychiatr Scand
  1995 Jan;91(1):69-70

This also has been known to happen with other psychoactive drugs: 

  Anderson-Hunt M; Dennerstein L; "Increased female sexual response after
  oxytocin" BMJ 1994 Oct 8;309(6959):929 -- also see comment in: BMJ 1994
  Oct 8;309(6959):891-2

  Stevenson RW; Solyom L; "The aphrodisiac effect of fenfluramine: two
  case reports of a possible side effect to the use of fenfluramine in
  the treatment of bulimia."  J Clin Psychopharmacol 1990 Feb;10(1):69-71

However, before you go trying to do this at home, note well that the vast
majority of sexual side effects of anti-depressant drugs are to decrease
sexual function and the ability to reach orgasm....

Larry



home help back first fref pref prev next nref lref last post