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Home-based work for you

daemon@ATHENA.MIT.EDU (jephthah millicen)
Sat Sep 15 15:34:38 2007

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From: "jephthah millicen" <esau@gardengatemag.com>
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Subject: Home-based work for you
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Yet, there remains a problem with the "nano" in both nanoscience and nanotechnology. "Nanotechnology's a term with not too much new in it. It existed a long time ago," says Dai. Indeed, the characteristic length of bonds that have always been under scrutiny in the molecular sciences is on the order of a nanometer. Chidsey adds, "I worry that the term confuses people about what's important: the length scale itself is not important." Rather, it is the novel properties that structures exhibit at the nanoscale that is. As Dai puts it, "We work on carbon nanotubes not because they are small, but because they are interesting. They just happen to be nano." For all the problems with the term nanotechnology, though, it may have done some good. Chidsey remarks, "Just as nanotechnology has attracted the attention of outsiders, it also stimulates us internally: it provides a context for tackling and defining grand challenges-things so out there you wouldn't tackle them otherwise."








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18 Stanford Scientific Review successfully demonstrated their use as highly sensitive toxic gas sensors, and with Professor Calvin Quate (Electrical Engineering), has commercialized nanotubes as scanning probe tips to increase probe resolution and tip durability. An area that Dai has just begun exploring is the drug delivery potential of carbon nanotubes. "The tube has a large surface area and is empty inside. So either you can attach the drug to the outer surface, or fill it up like a test tube," says Dai. Furthermore, multiple functional molecules can be attached to the surface: "Say, a molecule that fluoresces to tell you where the drug is in the cell and an antibody that specifically targets the site of drug delivery." So far, Dai reports that his research finds nanotubes to be quite "biologically friendly."
Nature's own marvelous nanoscale machines include motors that spin bacterial flagella at up to 1000 revolutions per second and polymerases that step along DNA and RNA to facilitate the flow of genetic information. Block, along with other Stanford researchers such as Professors W. E. Moerner (Chemistry) and Steve Chu (Physics), are studying Nature's machines through single molecule science. This young field is devoted to following molecules one at a time rather than observing their averaged behavior, as has been done traditionally. To understand why average properties may obscure molecular behavior, "Consider a ship traveling from New York to San Francisco," says Block. "If it's small enough, it will travel down into the Caribbean and go across the Panama Canal and then back up to San Francisco. If it's a big oil tanker, it won't fit through the Panama Canal; it's got to go all the way around Cape Horn. But the average path of a ship traveling from New York to San Francisco wo
 uld probably come out somewhere in the middle of the Amazon where there is in fact no route at all!"


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