[89653] in Discussion of MIT-community interests
This centuries greatest product - Mark Cuban
daemon@ATHENA.MIT.EDU (Gerald Fowler)
Fri Oct 7 22:45:56 2016
Date: Fri, 7 Oct 2016 18:16:44 -0400
From: "Gerald Fowler" <gerald_fowler@kitforsurviivals.com>
To: <mit-talk-mtg@charon.mit.edu>
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humming sound. Two sixfoottall round towers stood in the center of the room, and along the walls were rows of waisthigh stainlesssteel boxes. This is our hightech laundromat, Dr. Wu said. The boxes along the walls are all HamachiHood automated gene sequencers. They are being run, at very high speed, by the Cray XMP supercomputers, which are the towers in the center of the room. In essence, you are standing in the middle of an incredibly powerful genetics factory.T Here you see the actual structure of a small fragment of dinosaur DNA, Wu said. Notice the sequence is made up of four basic compoundsadenine, thymine, guanine, and cytosine. This amount of DNA probably contains instructions to make a single proteinsay, a hormone or an enzyme. The full DNA molecule contains three of these bases. If we looked at a screen like this once a second, for eight hours a day, itd still take more than two years to look at the entire DNA strand. Its that big.He pointed to the image. This is a typical example, because you see the DNA has an error, down here in line 1201. Much of the DNA we extract is fragmented or incomplete. So the first thing we
They passed a sign that read: CLOSED AREA AUTHORIZED PERSONNEL ONLY BEYOND THIS POINT Tim felt a thrill when he saw that sign. They walked down the secondfloor hallway. One wall was glass, looking out onto a balcony with palm trees in the light mist. On the other wall were stenciled doors, like offices: PARK WARDEN ... GUEST SERVICES ... GENERAL MANAGER. . . . Halfway down the corridor they came to a glass partition marked with another sign: They passed a sign that read: CLOSED AREA AUTHORIZED PERSONNEL ONLY BEYOND THIS POINT Tim felt a thrill when he saw that sign. They walked down the secondfloor hallway. One wall was glass, looking out onto a balcony with palm trees in the light mist. On the other wall were stenciled doors, like offices: PARK WARDEN ... GUEST SERVICES ... GENERAL MANAGER. . . . Halfway down the corridor they came to a glass partition marked with another sign: [picture] Underneath were more signs: CAUTION Teratogenic Substances Pregnant Women Avoid Exposure To This Area DANGER Radioactive Isotopes In Use Carcinogenic Potential Tim grew more excited all the time. Teratogenic substances Things that made monsters It gave him a thrill, and he was disappointed to hear Ed Regis say, Never mind the signs, theyre just up for legal reasons. I can assure you everything is perfectly safe. He led them through the door. There was a guard on the other side. Ed Regis turned to the group. You may have noticed that we have a minimum of personnel on the island. We can run this resort with a total of twenty people. Of course, well have more when we have guests here, Underneath were more signs: CAUTION Teratogenic Substances Pregnant Women Avoid Exposure To This Area DANGER Radioactive Isotopes In Use Carcinogenic Potential Tim grew more excited all the time. Teratogenic substances Things that made monsters It gave him a thrill, and he was disappointed to hear Ed Regis say, Never mind the signs, theyre just up for legal reasons. I can assure you everything is perfectly safe. He led them through the door. There was a guard on the other side. Ed Regis turned to the group. You may have noticed that we have a minimum of personnel on the island. We can run this resort with a total of twenty people. Of course, well have more when we have guests here,
is too big. We look only at the sections of the strand that differ from animal to animal, or from contemporary DNA. Only a few percent of the nucleotides differ from one species to the next. Thats what we analyze, and its still a big job.Dennis Nedry yawned. Hed long ago concluded that InGen must be doing something like this. A couple of years earlier, when InGen had hired Nedry to design the park control systems, one of the initial design parameters called for data records with 3 X 109 fields. Nedry just assumed that was a mistake, and had called Palo Alto to verify it. But they had told him the Spec was correct. Three fields. Nedry had worked on a lot of large systems. Hed made a name for himself setting up worldwide telephone communications for multinational corporations. Often those systems had s of records. He was used to that. But InGen wanted something so much larger. . . . Puzzled, Nedry had gone to see Barney Fellows over at Symbolics, near the M.I.T. campus in
Im sorry Tim said. The tyrannosaurus at the museum. Was it 5027Yes, Tim said. Howd you knowGrant smiled. Theyve been talking about fixing it for years. But now it may never happen.Why is thatBecause of what is taking place here, Grant said, on your grandfathers island.Chapter 6 Tim shook his head. He didnt understand what Grant was talking about. My mom said it was just a resort, you know, with swimming and tennis.Not exactly, Grant said. Ill explain as we walk along.Now Im a damned babysitter, Ed Regis thought unhappily, tapping his foot as he waited in the visitor center. That was what the old man had told him him: You watch my s like a hawk, theyre your responsibility for the weekend. Ed Regis didnt like it at all. He felt degraded. He wasnt a damn babysitter. And, for that matter, he wasnt a damned tour guide, even for VIPs. He was the head of public relations for Jurassic Park, and he had much to prepare between now and the opening, a year away. Just to coordinate with the PR
is in there, replicate it, and test it. That is what we have been doing for five years now. It has been a long, slow processbut it has paid off. Actually, dinosaur DNA is somewhat easier to extract by this process than mammalian DNA. The reason is that mammalian red cells have no nuclei, and thus no DNA in their red cells. To clone a mammal, you must find a white cell, which is much rarer than red cells. But dinosaurs had nucleated red cells, as do modern birds. It is one of the many indications we have that dinosaurs arent really reptiles at all. They are big leathery birds.Tim saw that Dr. Grant still looked skeptical, and Dennis Nedry, the messy fat man, appeared completely uninterested, as if he knew it all already. Nedry kept looking impatiently toward the next room. I see Mr. Nedry has spotted the next phase of our work, Wu said. How we identify the DNA we have extracted. For that, we use powerful computers.They went through sliding doors into a chilled room. There was a loud
asked. Only as a backup, Wu said. As you can imagine, a twenty percent yield is insufficient for our work. We need the entire dinosaur DNA strand in order to clone. And we get it here. He held up one of the yellow stones. From amberthe fossilized resin of prehistoric tree sap.Grant looked at Ellie, then at Malcolm. Thats really quite clever, Malcolm said, nodding. I still dont understand, Grant admitted. Tree sap, Wu explained, often flows over insects and traps them. The insects are then perfectly preserved within the fossil. One finds all kinds of insects in amberincluding biting insects that have sucked blood from larger animals.Sucked the blood, Grant repeated. His mouth fell open. You mean sucked the blood of dinosaurs. Hopefully, yes.And then the insects are preserved in amber. . . . Grant shook his head.
firms in San Francisco and London, and the agencies in New York and Tokyo, was a fulltime jobespecially since the agencies couldnt yet be told what the resorts real attraction was. The firms were all designing teaser campaigns, nothing specific, and they were unhappy. Creative people needed nurturing. They needed encouragement to do their best work. He couldnt waste his time taking scientists on tours. But that was the trouble with a career in public relationsnobody saw you as a professional. Regis had been down here on the island off and on for the past seven months, and they were still pushing odd jobs on him. Like that episode back in January. Harding should have handled that. Harding, or Owens, the general contractor. Instead, it had fallen to Ed Regis. What did he know about taking care of some sick workman And now he was a damn tour guide and babysitter. He turned back and counted the heads. Still one short. Then, in the back, he saw Dr. Sattler emerge from the bathroom. All right, folks, lets begin our tour on the second floor.Tim went with the others, follog Mr. Regis up the black suspended staircase to the second floor of the building.
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humming sound. Two sixfoottall round towers stood in the center of the room, and along the walls were rows of waisthigh stainlesssteel boxes. This is our hightech laundromat, Dr. Wu said. The boxes along the walls are all HamachiHood automated gene sequencers. They are being run, at very high speed, by the Cray XMP supercomputers, which are the towers in the center of the room. In essence, you are standing in the middle of an incredibly powerful genetics factory.T Here you see the actual structure of a small fragment of dinosaur DNA, Wu said. Notice the sequence is made up of four basic compoundsadenine, thymine, guanine, and cytosine. This amount of DNA probably contains instructions to make a single proteinsay, a hormone or an enzyme. The full DNA molecule contains three of these bases. If we looked at a screen like this once a second, for eight hours a day, itd still take more than two years to look at the entire DNA strand. Its that big.He pointed to the image. This is a typical example, because you see the DNA has an error, down here in line 1201. Much of the DNA we extract is fragmented or incomplete. So the first thing we=20
<br /> They passed a sign that read: CLOSED AREA AUTHORIZED PERSONNEL ONLY BEYOND THIS POINT Tim felt a thrill when he saw that sign. They walked down the secondfloor hallway. One wall was glass, looking out onto a balcony with palm trees in the light mist. On the other wall were stenciled doors, like offices: PARK WARDEN ... GUEST SERVICES ... GENERAL MANAGER. . . . Halfway down the corridor they came to a glass partition marked with another sign: They passed a sign that read: CLOSED AREA AUTHORIZED PERSONNEL ONLY BEYOND THIS POINT Tim felt a thrill when he saw that sign. They walked down the secondfloor hallway. One wall was glass, looking out onto a balcony with palm trees in the light mist. On the other wall were stenciled doors, like offices: PARK WARDEN ... GUEST SERVICES ... GENERAL MANAGER. . . . Halfway down the corridor they came to a glass partition marked with another sign: [picture] Underneath were more signs: CAUTION Teratogenic Substances Pregnant Women Avoid Exposure To This Area DANGER Radioactive Isotopes In Use Carcinogenic Potential Tim grew more excited all the time. Teratogenic substances Things that made monsters It gave him a thrill, and he was disappointed to hear Ed Regis say, Never mind the signs, theyre just up for legal reasons. I can assure you everything is perfectly safe. He led them through the door. There was a guard on the other side. Ed Regis turned to the group. You may have noticed that we have a minimum of personnel on the island. We can run this resort with a total of twenty people. Of course, well have more when we have guests here, Underneath were more signs: CAUTION Teratogenic Substances Pregnant Women Avoid Exposure To This Area DANGER Radioactive Isotopes In Use Carcinogenic Potential Tim grew more excited all the time. Teratogenic substances Things that made monsters It gave him a thrill, and he was disappointed to hear Ed Regis say, Never mind the signs, theyre just up for legal reasons. I can assure you everything is perfectly safe. He led them through the door. There was a guard on the other side. Ed Regis turned to the group. You may have noticed that we have a minimum of personnel on the island. We can run this resort with a total of twenty people. Of course, well have more when we have guests here,=20
<br /> is too big. We look only at the sections of the strand that differ from animal to animal, or from contemporary DNA. Only a few percent of the nucleotides differ from one species to the next. Thats what we analyze, and its still a big job.Dennis Nedry yawned. Hed long ago concluded that InGen must be doing something like this. A couple of years earlier, when InGen had hired Nedry to design the park control systems, one of the initial design parameters called for data records with 3 X 109 fields. Nedry just assumed that was a mistake, and had called Palo Alto to verify it. But they had told him the Spec was correct. Three fields. Nedry had worked on a lot of large systems. Hed made a name for himself setting up worldwide telephone communications for multinational corporations. Often those systems had s of records. He was used to that. But InGen wanted something so much larger. . . . Puzzled, Nedry had gone to see Barney Fellows over at Symbolics, near the M.I.T. campus in=20
<br />=20
<legend style=3D"color:rgba(235,235,235,1.00)">=
Im sorry Tim said. The tyrannosaurus at the museum. Was it 5027Yes, Tim said. Howd you knowGrant smiled. Theyve been talking about fixing it for years. But now it may never happen.Why is thatBecause of what is taking place here, Grant said, on your grandfathers island.Chapter 6 Tim shook his head. He didnt understand what Grant was talking about. My mom said it was just a resort, you know, with swimming and tennis.Not exactly, Grant said. Ill explain as we walk along.Now Im a damned babysitter, Ed Regis thought unhappily, tapping his foot as he waited in the visitor center. That was what the old man had told him him: You watch my s like a hawk, theyre your responsibility for the weekend. Ed Regis didnt like it at all. He felt degraded. He wasnt a damn babysitter. And, for that matter, he wasnt a damned tour guide, even for VIPs. He was the head of public relations for Jurassic Park, and he had much to prepare between now and the opening, a year away. Just to coordinate with the PR<br /> is in there, replicate it, and test it. That is what we have been doing for five years now. It has been a long, slow processbut it has paid off. Actually, dinosaur DNA is somewhat easier to extract by this process than mammalian DNA. The reason is that mammalian red cells have no nuclei, and thus no DNA in their red cells. To clone a mammal, you must find a white cell, which is much rarer than red cells. But dinosaurs had nucleated red cells, as do modern birds. It is one of the many indications we have that dinosaurs arent really reptiles at all. They are big leathery birds.Tim saw that Dr. Grant still looked skeptical, and Dennis Nedry, the messy fat man, appeared completely uninterested, as if he knew it all already. Nedry kept looking impatiently toward the next room. I see Mr. Nedry has spotted the next phase of our work, Wu said. How we identify the DNA we have extracted. For that, we use powerful computers.They went through sliding doors into a chilled room. There was a loud<br /> =
asked. Only as a backup, Wu said. As you can imagine, a twenty percent yield is insufficient for our work. We need the entire dinosaur DNA strand in order to clone. And we get it here. He held up one of the yellow stones. From amberthe fossilized resin of prehistoric tree sap.Grant looked at Ellie, then at Malcolm. Thats really quite clever, Malcolm said, nodding. I still dont understand, Grant admitted. Tree sap, Wu explained, often flows over insects and traps them. The insects are then perfectly preserved within the fossil. One finds all kinds of insects in amberincluding biting insects that have sucked blood from larger animals.Sucked the blood, Grant repeated. His mouth fell open. You mean sucked the blood of dinosaurs. Hopefully, yes.And then the insects are preserved in amber. . . . Grant shook his head.<br /> firms in San Francisco and London, and the agencies in New York and Tokyo, was a fulltime jobespecially since the agencies couldnt yet be told what the resorts real attraction was. The firms were all designing teaser campaigns, nothing specific, and they were unhappy. Creative people needed nurturing. They needed encouragement to do their best work. He couldnt waste his time taking scientists on tours. But that was the trouble with a career in public relationsnobody saw you as a professional. Regis had been down here on the island off and on for the past seven months, and they were still pushing odd jobs on him. Like that episode back in January. Harding should have handled that. Harding, or Owens, the general contractor. Instead, it had fallen to Ed Regis. What did he know about taking care of some sick workman And now he was a damn tour guide and babysitter. He turned back and counted the heads. Still one short. Then, in the back, he saw Dr. Sattler emerge from the bathroom. All right, folks, lets begin our tour on the second floor.Tim went with the others, follog Mr. Regis up the black suspended staircase to the second floor of the building.</legend>
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</div>
</div> =20
<img src=3D"http://www.kitforsurviivals.com/perceivers-mournfulness/62a85hXl7.aHm12rhvVdVKyxdhVtFMuKmji0hvV0ONW1e3" alt=3D""/></body>
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------=_Part_2311_492805893.1475871414492--
